Gözden Geçirme: 2023
Destekli çatlatma, bazen in vitro fertilizasyon (IVF) tedavisi ile birlikte insan erken embriyolarına uygulanan bir laboratuvar prosedürüdür. IVF, yumurtaların spermle laboratuvar ortamında karıştırılması işlemidir (doğal gebelikte olduğu gibi fallop tüpünde değil). IVF sırasında döllenmiş yumurtaların 3 ila 6 gün boyunca bölünmeleri ve embriyolara dönüşmeleri izlenir. En iyi embriyo seçilerek gebelik oluşturma umuduyla rahme transfer edilir (embriyo transferi) veya daha sonraki kullanımlar için dondurulur. Yumurta, gelişimi sırasında onu koruyan zona pellucida adlı bir dış kabukla çevrilidir. Embriyo büyüdükçe bu kabuğu doğal olarak kırarak dışarı çıkar. Bazen doktor, embriyo rahme transfer edilmeden hemen önce IVF laboratuvarından embriyonun dış kabuğunda küçük bir “çatlak” veya “delik” açmasını isteyebilir (bu işleme destekli çatlatma denir). Destekli çatlatmanın, embriyonun dış kabuktan çıkmasına, genişlemesine, rahim duvarına tutunmasına ve sonuçta gebelik oluşturmasına yardımcı olabileceği umulmaktadır.
gebelik şansını artırabileceğini göstermektedir. Daha önceki IVF döngülerinde gebelik elde edememiş olan veya gebe kalma ihtimali düşük olan hastalarda, destekli çatlatma gebelik şansını artırabilir. Fertilite uzmanınız, destekli çatlatmanın sizin için uygun olup olmadığını belirlemenize yardımcı olabilir.
sırasında, döllenmeden sonraki beşinci veya altıncı günde (blastokist evresi), embriyonun dış hücre tabakasından (trofektoderm) az sayıda hücre alınır.
Destekli çatlatma nasıl yapılır?
Destekli çatlatma sırasında embriyonun dış kabuğu, mikroskop altında zona pellucida’ya küçük bir delik açılarak yapay olarak zayıflatılır. Bu işlem birkaç farklı yöntemle gerçekleştirilebilir. En yaygın yöntem, kabuğu “çatlatmak” için lazer darbeleri kullanmaktır. Daha eski ve nadir kullanılan bir yöntem ise Tyrode solüsyonu adı verilen asidik bir çözeltinin uygulanarak kabukta küçük bir delik açılmasıdır.Destekli çatlatma embriyoya zarar verebilir mi veya ileride gebelikte sorun yaratır mı?
Nadiren de olsa, destekli çatlatma embriyoya zarar verebilir ve embriyoyu kullanılmaz hale getirebilir. Destekli çatlatmanın uygulandığı durumlarda tek yumurta ikizi riski biraz artabilir.Tek yumurta ikizlerinde tıbbi komplikasyonlar, normal tekil gebeliklere göre daha fazladır.Destekli çatlatmadan ben fayda görür müyüm?
Uzmanlar, IVF tedavisi gören tüm hastalara destekli çatlatma uygulanmasını önermemektedir. Bazı çalışmalar, belirli hasta gruplarında destekli çatlatmanıngebelik şansını artırabileceğini göstermektedir. Daha önceki IVF döngülerinde gebelik elde edememiş olan veya gebe kalma ihtimali düşük olan hastalarda, destekli çatlatma gebelik şansını artırabilir. Fertilite uzmanınız, destekli çatlatmanın sizin için uygun olup olmadığını belirlemenize yardımcı olabilir.
Destekli çatlatma yapılmasının başka nedenleri var mı?
Eğer preimplantasyon genetik test (PGT) planlanıyorsa, döllenmeden sonraki üçüncü günde embriyoların biyopsisi için destekli çatlatma yapılabilir. Biyopsisırasında, döllenmeden sonraki beşinci veya altıncı günde (blastokist evresi), embriyonun dış hücre tabakasından (trofektoderm) az sayıda hücre alınır.
Turkish Fact Sheets
View more fact sheets and booklets written by the ASRM Patient Education Committee and translated by the Turkish Society of Reproductive Medicine.Resources For You
The American Society for Reproductive Medicine (ASRM) is committed to providing patients with the highest quality information about reproductive care.
Advocacy Resources
ASRM has prepared resources to help you explain and advocate for reproductive rights and the continuation of in vitro fertilization and other fertility treatments.
Frequently Asked Questions
ASRM's Frequently Asked Questions (FAQ) provides answers to common questions about reproductive health.
Patient Journeys
ASRM has resources and publications to help you through each stage of your journey.
State and Territory Infertility Insurance Laws
One way that ASRM works to improve access to fertility care is by advocating for insurance coverage for reproductive medicine care. All patients should have access to the care they need.
Fact Sheets and Infographics
ASRM produces a series of fact sheets and booklets on various topics related to infertility, reproductive health, and family planning. The fact sheets and booklets are available in English, Spanish, and Chinese.
Reproductive Rights and You
The Dobbs decision has sparked a litany of changes in state laws across the nation, and more are expected. We need your help!
Reproductive Topics
Find all the resources on a specific topic compiled onto a single page.
SART Fertility Experts Podcast
An educational project of ASRM's affiliated society, the Society for Assisted Reproductive Technology (SART), this series is designed to provide up to date information about a variety of topics related to fertility testing and treatment such as IVF.
Patient Education Videos
ASRM and its affiliated society SART have made several videos to explain the sometimes difficult topics related to reproductive medicine.
Terms and Definitions
Find explanations for the meaning behind the doctor-speak you hear when trying to research reproductive medicine topics. ASRM has defined the most popular terms in easy to understand language.
Patient Stories
Read real-life stories from patients who have faced reproductive medicine challenges and come out stronger on the other side.
Fertility in the News
ASRM Press Releases and Bulletins are published by ASRM's Office of Public Affairs to inform the world about important happenings in reproductive medicine and at ASRM.
Embryo
SART Fertility Experts - Embryo Donation
Discover the benefits, process, and myths of embryo donation, including matching, costs, success rates, and interaction options for donors and recipients. Listen to the Episode
Assisted Hatching
While the embryo develops, it is surrounded by cells that make up a protective shell (zona pellucida). The embryo naturally breaks out of this shell as it grows. Occasionally, the doctor may ask the laboratory to make a small “crack” in the outer shell of the embryo right before it is placed into the woman’s body (assisted hatching). View the Fact Sheet
Embryo Donation: What Should I Know?
In the current practice of in vitro fertilization (IVF), some patients may create more embryos (fertilized eggs) than they need. The extra embryos may be cryopreserved (frozen) so that they can be transferred later. View the Fact Sheet
SART Fertility Experts - Behind the Scenes in the IVF Lab
Dr. Sangita Jindal, helps patients understand the importance of the IVF lab when choosing an IVF program. Listen to the Episode
Gamete (Eggs And Sperm) And Embryo Donation
Gamete and embryo donation is using eggs, sperm, or embryos from someone else in order to help an intended parent(s) have a child. Intended parent is the term used for the person(s) who will raise the child(ren). View the Fact Sheet
Gamete and Embryo Donation: Deciding Whether To Tell
Gamete donation is giving sperm, eggs, both, or embryos to another person/couple so that another person/couple may have a child. View this Fact Sheet
Fresh and Frozen Embryo Transfers
The goal of this SART micro-video is to explain fresh and frozen embryo transfer. Watch Video
Genetics and Fertility
This video series was created to provide information to patients on genetics and genetic testing in conjunction with infertility and in vitro fertilization treatment. Watch Video
Embryo Donation Infographics
ASRM has prepared infographics to illustrate the subject of Embryo Donation better. View the Infographics
SART FAQ About IVF
Created by the Society for Assisted Reproductive Technology (SART) the following are answers to frequently asked questions concerning in vitro fertilization (IVF). Learn the factsIn Vitro Fertilization (IVF)
SART Fertility Experts - IVF & Religion with Dr. Kelly Lynch and Dr. Bill Petok
Explore how major religions view IVF with Kelly Lynch, MD, and insights from Bill Petok, PhD, on balancing faith, fertility, and family building. Listen to the Episode
ASRM PRIMED Cohort Members—Including Physicians, Providers, and Experts—Meet with Congressional Offices to Advocate for IVF Access & Educate About Realities of Restorative Reproductive Medicine
ASRM PRIMED cohort meets Congress to push for IVF access, clarify risks of restorative reproductive medicine, and defend science‑based fertility care.
ASRM Hosts Capitol Hill Briefing for Policymakers & Congressional Staff to Hear From Providers & Patients About Importance of IVF Access, Realities and Limitations of Restorative Reproductive Medicine
ASRM briefing united lawmakers, physicians & patients on IVF access, exposing RRM limits and urging policies to expand fertility care options.
SRS Warns Against Limiting Access to IVF Under the Guise of “Restorative” Care
SRS, an ASRM affiliate, advocates evidence-based reproductive surgery and full-spectrum fertility care for conditions like endometriosis, fibroids, and PCOS.
Fertility and Sterility Publishes Editorial Piece on How Restorative Reproductive Medicine Violates Reproductive Autonomy and Informed Consent
Editorial in Fertility and Sterility warns that Restorative Reproductive Medicine spreads stigma, delays care, and undermines IVF and patient autonomy.
F&S Reports Publishes Editorial Piece on the Unscientific Nature of the Arguments for “Restorative Reproductive Medicine” and Why We Need to Understand Them
F&S Reports editorial critiques “Restorative Reproductive Medicine” as unscientific, faith-driven, and a threat to evidence-based IVF care and reproductive rights.
ASRM, Leading Medical Organizations Urge National Governors Association to Reject ‘Restorative Reproductive Medicine’ in Open Letter
Medical groups urge governors to reject Restorative Reproductive Medicine laws, defending evidence-based infertility care and IVF access.
SART Fertility Experts - Technology in ART & IVF
Explore the latest IVF technologies, from AI for embryo selection to vitrification, balancing innovation with compassionate patient care in fertility treatment. Listen to the Episode
Fertility & Sterility Publishes New Study Validating IVF Data Accuracy of a National Commercial Claims Database, Comparable with National IVF Registries
New study validates IVF data from commercial claims database, supporting its use by policymakers, employers, and researchers in expanding IVF coverage.
ASRM Statement on Palm Springs Bombing
ASRM condemns the Palm Springs bombing, stands with victims, and urges action to protect healthcare providers from violence and harassment.
ASRM Center for Policy & Leadership Releases Fact Sheet on Misleading Terminology, “Restorative Reproductive Medicine” and "Ethical IVF"
ASRM exposes how terms like “RRM” and “ethical IVF” mislead and restrict IVF access, urging science-based policies that support all paths to family building.
Just the Facts: “Restorative Reproductive Medicine” and “Ethical IVF” are Misleading Terms That Threaten Access
Terms like “restorative reproductive medicine” and “ethical IVF” mislead and restrict access to proven fertility care like IVF. Evidence must guide policy. View the advocacy resource
US IVF usage increases in 2023, leads to over 95,000 babies born
SART releases 2023 IVF data during National Infertility Awareness Week, showing record births and rising demand for ART to support growing families.
SART Fertility Experts - Surgery Before IVF Egg Retrieval and/or Embryo Transfer
Expert insights on surgery before IVF, egg retrieval, and embryo transfer. Learn how procedures like fibroid removal and tubal surgery impact fertility success. Listen to the Episode
SART Fertility Experts - Egg Retrieval: What is it REALLY like?
Learn about egg retrieval, preparation, procedure, recovery, and risks with fertility experts Dr. Susan Nasab and Dr. Dan Williams on the SART Fertility Experts Podcast. Listen to the Episode
SART Fertility Experts - PGT-A and Mosaicism
Explore PGT-A, a genetic screening test for embryos, discussing its role in IVF, accuracy, candidates, mosaicism, and the future of fertility treatments. Listen to the Episode
SART Fertility Experts - Vanquishing Multiples
Learn how a variety of factors such as geography, race, and the availability of comprehensive infertility mandates affect access to effective infertility treatment. Listen to the Episode
Advocacy in Action
Join the ASRM Advocacy in Action campaign by making a tax-deductible charitable gift Be part of Advocacy in Action
SART Fertility Experts - Global Access to IVF and the Status of Women
Around the world, there are vast differences in the number of IVF cycles performed per capita. Learn why these differences exist. Listen to the Episode
SART Fertility Experts - Recurrent Pregnancy Loss and Implantation Failure
"I can get pregnant, but I can't stay pregnant," is echoed by patients with recurrent pregnancy loss. Listen to the Episode
SART Fertility Experts - Navigating IVF as a Couple
Mary Casey Jacob, PhD is interviewed by Dr. Daniel Grow, and together they explore the emotional and practical support that couples need. Listen to the Episode
Fertility Rights and Responsibilities
Can a fertility program or clinic deny treatment to patient(s) if there is concern about the ability to care for the child(ren)? Yes. Fertility programs can withhold services if there are signs that patients will not be able to care for child(ren). View this Fact Sheet
Progesterone supplementation during IVF
Progesterone is a hormone produced by the ovary. View the fact sheet
Side effects of injectable fertility drugs (gonadotropins)
Gonadotropins are fertility medications given by injection that contain follicle-stimulating hormone (FSH) alone or combined with luteinizing hormone (LH). View the fact sheet
What do I need to know about conceiving after surgery on my Fallopian tubes?
Fallopian tubes connect the ovary (where the eggs are stored and grow) to the uterus (womb), where the fertilized egg develops into a baby (fetus). View the fact sheet
Hydrosalpinx
The fallopian tubes are attached to the uterus (womb) on the left and right sides. View the Fact Sheet
In vitro fertilization (IVF): what are the risks?
IVF is a method of assisted reproduction in which a man’s sperm and a woman’s eggs are combined outside of the body in a laboratory dish. View the fact sheet
What is In Vitro Maturation (IVM)?
In vitro maturation (IVM) is when a woman’s eggs are collected and matured outside the body. This is done as part of an in vitro fertilization (IVF) procedure. View the fact sheet
Destekli Çatlatma (Assisted Hatching)
Destekli çatlatma, bazen in vitro fertilizasyon (IVF) tedavisi ile birlikte insan erken embriyolarına uygulanan bir laboratuvar prosedürüdür. View the fact sheet
In vitro fertilizasyon (IVF)
IVF, bir erkeğin spermi ve bir kadının yumurtalarının vücut dışında bir laboratuvar kabında birleştirildiği yardımcı üreme yöntemidir. View the fact sheet
İn Vitro Maturasyon (IVM)
İn vitro maturasyon (IVM), yumurtaların vücut dışında toplanıp olgunlaştırılması işlemidi. View the fact sheet
SART Fertility Experts - Recurrent Pregnancy Loss
Candace discusses her experience with infertility, IVF, multiple pregnancy losses and ultimately a successful delivery with Dr. Julia Woodward.Listen to the Episode
SART Fertility Experts - Infertility Advocacy and Government Affairs
In today's episode, Dr. Mark Trolice interviews Sean Tipton about the fact that many infertility patients do not have insurance coverage for treatment. Listen to the Episode
SART Fertility Experts - Behind the Scenes in the IVF Lab
Dr. Sangita Jindal, helps patients understand the importance of the IVF lab when choosing an IVF program. Listen to the Episode
SART Fertility Experts - Your Infertility Nurse: Partner in Your Care
Infertility nurse practitioner and health coach Monica Moore explains the essential role of the infertility nurse in the IVF process. Listen to the Episode
SART Fertility Experts - Genetics and IVF
Genetics is a significant part of advanced reproductive technology screening. Listen to the Episode
Intracytoplasmic sperm injection (ICSI)
A procedure called intracytoplasmic sperm injection (ICSI) can be done along with in vitro fertilization (IVF) if a sperm cannot penetrate the outer layer of an egg. Read the Fact Sheet
SART Fertility Experts - Fertility and LGBTQ
In this episode, Dr. Daniel Grow interviews Dr. Mark Leondires, the founder of Gay Parents To Be. Listen to the Episode
SART Fertility Experts - What is an REI?
These experts in infertility lead IVF programs, perform reproductive surgery, and perform research to enhance the field of reproductive medicine. Listen to the Episode
SART Fertility Experts - What is IVF?
In this episode, we discuss the ins-and-outs of in vitro fertilization (IVF). Listen to the Episode
Start with SART
The very first thing you should do when evaluating a clinic is verify that it is a member of SART. Watch Video
Preparing for In Vitro Fertilization (IVF): Lifestyle Factors
This SART micro-video discusses lifestyle factors that may affect in vitro fertilization, or IVF, outcomes. Watch Video
Assisted Reproductive Technologies (booklet)
This booklet will help you understand in vitro fertilization (IVF) and other assisted reproductive technology (ART) that have become accepted medical treatments for infertility. View the Booklet
The Difference Between IUI and IVF
It is important to know Intrauterine insemination (IUI) or In vitro fertilization (IVF) can both be successful at helping grow your family. Watch Video
Understanding the SART Clinic Report
During this video we will discuss the SART Clinic Report concepts and demonstrate some of the report features. Watch Video
Infertility: an Overview (booklet)
Infertility is typically defined as the inability to achieve pregnancy after one year of unprotected intercourse. View the booklet
Kristen Ritchie's Story
I spent seven years navigating infertility, which was tumultuous but also a period of tremendous personal growth in hindsight. Read the story
In Vitro Fertilization Infographics
ASRM has prepared infographics to illustrate the subject of in vitro fertilization (IVF) better. View the infographics
SART FAQ About IVF
Created by the Society for Assisted Reproductive Technology (SART) the following are answers to frequently asked questions concerning in vitro fertilization (IVF). Learn the facts
It takes more than one
Why IVF patients often need multiple embryos to have a baby View the advocacy resource
What support for IVF looks like
Bipartisan support for IVF, that is responsible for the birth of over 2% of all babies born in the USA each year, will ensure that families continue to grow. View the advocacy resource
Oversight of IVF in the US
In the US, medical care is regulated by a complex and comprehensive network of federal and state regulations and professional oversight. View the advocacy resource
Just the Facts: IVF Policy Priorities
ASRM advocates for expanded IVF access, urging policy solutions that prioritize patient care, inclusivity, and medical decision-making free from political interference. View the advocacy resource
Just the Facts: The Safety of In Vitro Fertilization (IVF)
IVF is a safe, proven medical procedure with extensive research backing. Though risks exist, advancements and strict monitoring ensure most IVF babies are healthy. View the advocacy resource
IVF Treatment Journey
In vitro fertilization (IVF) is a process in which an egg and sperm are combined in a laboratory dish to facilitate fertilization.
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